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VSC is Flanders' most highly integrated high-performance research computing environment, connecting universities, research centers, and industry to shared compute infrastructure.

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Research

High-performance computing (HPC) started to gain traction in the 1990s with the introduction of massively parallel computer systems. Thanks to steadily increasing compute power and widespread availability of HPC infrastructure, HPC quickly became an essential component in nearly every field of scientific research. HPC is now firmly established as the third pillar of modern research, alongside theory and experimentation.

Private Sector

Today, HPC usage by large companies is widespread in the areas of manufacturing, aerospace, oil & gas, life sciences, and information technology. The classical usage for HPC is advanced 3D modeling and simulation, which is understandable when building things that need to fit together in assemblies and systems.

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Latest News & Events

VSC's new Tier-1 supercomputer sofia ranks among the world's most powerful and energy-efficient systems

The VSC Tier-1 supercomputer sofia has made a strong international debut, ranking 222nd in the TOP500 list of the world's most powerful supercomputers and 41st in the Green500 ranking for energy efficiency. Hosted by VUB at the Nexus Datacenter in Zellik, sofia combines advanced computing power with a strong focus on sustainability. Starting in July 2026, it will support Flemish researchers in AI, climate science, medical research, and large-scale simulations.

Flemish Supercomputer Center Publishes Annual Report 2025: A Year of New Power, Growing Demand, and Bold Ambition

The Flemish Supercomputer Center (VSC) has published its Annual Report 2025, highlighting a year of major milestones, including the inauguration of sofia, VSC's next-generation Tier-1 supercomputer. The report showcases how VSC continues to support cutting-edge research, AI, and innovation through advanced computing infrastructure, expert support, training, and European collaborations. Discover the achievements, impact, and future ambitions shaping the HPC landscape in Flande

KU Leuven/UHasselt HPC User Day 2026 Marks Successful Launch of New Tier-2 Supercomputer

Highlights from the KU Leuven/UHasselt HPC User Day 2026, featuring the inauguration of the new Tier-2 supercomputer, hands-on training sessions, research testimonials, and community networking.

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Events

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Research Showcase

A Rigorous and Direct Route to Gibbs Free Energies of Solids

Predicting the stability of crystalline materials is essential for developing advanced materials and pharmaceuticals. Researchers developed a new thermodynamic integration framework that calculates Gibbs free energies entirely under constant-pressure conditions, improving accuracy while simplifying the workflow. The method was validated using ice polymorphs and CsPbI₃ and relied on more than 10,000 GPU hours on VSC infrastructure.

Multiomics immune profiling of a patient-relevant orthotopic lung cancer model using SEPARATE-Seq

Researchers at VUB developed a patient-relevant orthotopic lung cancer model and combined SEPARATE-Seq with spatial transcriptomics to map the immune landscape of lung tumours. Supported by VSC's high-performance computing infrastructure, the study provides new insights into immune cell behavior and offers a valuable resource for cancer immunology and future therapy development.

Impact of Dangling Bonds on the Electronic Structure of III-V Quantum Dots

Researchers at Ghent University used large-scale simulations on the Flemish Supercomputer Center (VSC) to investigate how dangling bonds influence the electronic structure of III-V quantum dots. Their findings reveal how surface defects affect semiconductor performance and identify promising materials for next-generation infrared sensors, imagers, and optoelectronic devices. This research advances the design of safer, high-performance quantum dot technologies.

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Research Showcase